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While direct evidence from human clinical trials is currently limited, a study on donor selection for FMT in UC revealed that successful FMT donor microbiomes exhibited higher oxygen tolerance, indicating the importance of facultative anaerobes in re-establishing an anaerobic environment to counteract ROS (239)

Novel place recognition Before the novel place recognition (NPR) test, the mice were subjected to sufficient handling and were concurrently habituated to an open field test (OFT) in a square chamber (40 40 40 cm)

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This adaptation can also contribute to resistance against therapies that induce oxidative stress or ferroptosis, supporting tumor growth and complicating treatment outcomes