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Nat Rev Gastroenterol Hepatol 16(2):79-80, 2019

Administration of DMF in vitro causes a rise in the concentration of succinate (42, 43)

Inflammatory macrophages are the major contributor to necrotic core formation, yet TREM2+ macrophages have recently been shown to have low expression of inflammatory genes and a beneficial role in atherosclerosis 97,98,99,100,101,102