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Description

A ferroptosis defense mechanism mediated by glycerol-3-phosphate dehydrogenase 2 in mitochondria

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For the vascular side, GHK-Cu promotes angiogenesis through VEGF and bFGF expression, improves blood vessel integrity, and supports microcirculation

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Ultimately, this FOXO4-DRI-mediated mechanism selectively eliminates senescent endothelial cells, which in turn attenuates vascular inflammation and improves endothelial-dependent vasodilation, conferring a significant protective effect on vascular function

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