glutathione peroxidase selenium cofactor PRDX6 dictates ferroptosis sensitivity by directing cellular utilization: Molecular Cell and the healthy functioning of the liver The Selenoprotein Glutathione Peroxidase 4:

Correlating longitudinal multi-omics data from large, well-annotated patient cohorts with clinical outcomes will thus enable accurate patient stratification, guide therapeutic decision-making, and increase the success rate of clinical trials

Tumor cells are generally characterized by altered redox homeostasis (Valko et al

Most of the studies either did not detect aspartame or detected it only at low concentrations

Lipoxygenases generate highly reactive peroxidation products of unsaturated fatty acids prone to further lipid peroxidation and GPX4 reduces lipid peroxidation products in membranes to stable hydroxyl-derivatives ( Gpx4 -knockout mice are phenotypically characterized by ineffective erythropoiesis ( The Role of GSH Depletion and GPX4 in Ferroptosis Ferroptosis has recently emerged as a new cell death modality