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Friedberg and Choi [124] conducted a 28-day pilot randomized blinded trial in 23 ME/CFS patients and found that daily hydrogen water supplementation did not improve self-reported fatigue compared to placebo

Eur J Surg Oncol 47(7):1552-1557, 2021

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Community-derived FOXO4-DRI daily dosing ladder Week Weeks 1-4 Daily Dose 250 mcg Week Weeks 5-8 Daily Dose 375 mcg Week Weeks 9-12 Daily Dose 500 mcg Week Weeks 13-16 Daily Dose 500 mcg Reported community dosing only