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In addition, PHD2 inhibits eEF2K to promote eEF2 activity 46,47

Results HRASV12- and cyclin E1-induced replication stress is mainly caused by R-loops To study the molecular mechanisms underlying oncogene-induced replication stress, we used pBABEneo-based retroviral vectors for overexpression of HRASV12 and cyclin E1, respectively, in human cells (Supplementary Fig

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