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& Kondratov, R

Treatment with Centella asiatica extract inhibits the expression of interleukin-6 (IL-6) and tumor necrosis factor- (TNF-) in a dose-dependent manner in inflammatory HaCaT cells, stimulated by interferon- (IFN-) and TNF--triggered inflammation

The molecular docking and dynamics studies revealed that DSF formed a stable complex with PIK3 via interactions with residues Ile932, Ile800, Ile848, Met772, and Trp780, which contributed significantly to stability

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